Antibody Any ELISA

Skip the Protein Prep.

Traditional ELISA systems require time-consuming protein expression, purification, and plate coatingslowing down research and limiting adaptability.

tANCHOR changes the game.

This innovative cell-based platform enables the display of antigen on the surface of cells, allowing for rapid, scalable, and highly specific antibody testing.

SARS-CoV-2 is a prime example.
To detect antibodies against new viral variants, tANCHOR requires only the RBD coding sequence to be cloned into the tANCHOR vector and introduced into HeLa cells. Within days, researchers can test sera from vaccinated or convalescent individuals without the need for recombinant protein purification and ELISA plate coating.

But the power of tANCHOR goes far beyond COVID-19.

Whether you’re studying viral antigens, bacterial epitopes, tumor-associated proteins, or autoimmune targets, tANCHOR is your plug-and-play solution for:

• Rapid antigen display and antibody binding analysis.

• Streamlined workflows without protein purification.

• Easy adaptation to new antigen targets.

One platform. Unlimited possibilities.

Reference

Ivanusic D. and Banert N. Protocol for monitoring of neutralizing antibodies to various receptor-binding domains using the tANCHOR system, STAR Protoc. 2025 Jul 2;6(3):103926.

Bernauer H., Maier J, Bannert N., Ivanusic D. Analysis of antibodies from whole-cell immunization by a tANCHOR cell-based ELISA, MicroPubl Biol. 2024 Apr 17:2024:10.17912.

Bernauer H., Maier J, Bannert N., Ivanusic D. tANCHOR cell-based IgG ELISA for the receptor binding domain of SARS CoV-2 variants. Oxford Academic Press Biology Methods and Protocols, 2024, bpae001.

Ivanusic D., Madela K., Burghard H., Holland G., Laue M., Bannert N. tANCHOR: a novel mammalian cell surface peptide display system. Biotechniques. 2021 Jan;70(1):21-28.

Ivanusic D., Pietsch H., König J., Denner J., Absence of IL-10 production by human PBMCs co-cultivated with human cells expressing or secreting retroviral immunosuppressive domains. PLoS One. 2018 Jul 12;13(7):e0200570.

Fast. Flexible.

For Research Use Only